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Create file sorry, your browser is unsupported so ncbi web applications may not function properly. More information. Ann surg oncol. Buy viagra online uk4 2012 jul;19(7):2360-6. Epub 2012 jan 21. Merkel cell carcinoma of unknown primary origin. Deneve jl, messina jl, marzban ss, gonzalez rj, walls bm, fisher kj, chen ya, cruse cw, sondak vk, zager js. Source department of cutaneous oncology, moffitt cancer center, tampa, fl, usa. Abstract background: merkel cell carcinoma (mcc) is a rare neuroendocrine tumor of the skin. Mcc from an unknown primary origin (mccup) can present a diagnostic and therapeutic challenge. We describe our single-institution experience with the diagnosis and management of mccup presenting as metastases to lymph nodes. Methods: after institutional review board approval, our institutional database spanning the years 1998-2010 was queried for patients with mccup. Clinicopathologic variables and outcomes were assessed. Results: from a database of 321 patients with mcc, 38 (12%) were identified as having nodal mccup. Median age was 67â years, and 79% were men. Nodal basins involved at presentation were cervical (58%), axillary/epitrochlear (21%), or inguinal/iliac (21%). order viagra overnight Ck20 staining was positive in 93% of tumors tested, and all were negative for thyroid transcription factor-1. Twenty-nine patients (76%) underwent complete regional lymph node dissection (lnd): 3 had lnd alone, ten had lnd and adjuvant radiotherapy, and 16 underwent lnd followed by chemoradiotherapy. Buy viagra cialis Definitive chemoradiotherapy without surgery was provided to six patients (16%), while radiotherapy alone was provided to three (8%). Recurrence was observed in 34% of patients. Median recurrence-free survival was 35â months. Discount viagra no prescription Ten patients (26%) died, five of disease and five of other causes. The median overall survival was 104â months. Conclusions: nodal mccup is a rare disease affecting primarily elderly white men. Recurrence is observed in approximately one-third of patients, with a 104â month median overall survival after a multimodal treatment approach consisting of surgery along with adjuvant chemotherapy and radiotherapy in the majority of patients. Pmid: 22271206 [pubmed - in process] linkout - more resources full text sources springer ebsco ohiolink electronic journal center miscellaneous swets information services supplemental content save items add to favorites loading related citations in pubmed nodal basin recurrence following lymph node dissection for melanoma: implications for adjuvant radiotherapy. [int j radiat oncol biol phys. ] nodal basin recurrence following lymph node dissection for melanoma: implications for adjuvant rad. Generic viagra pictures
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    I went one of the best Japanese restaurants (Sagami) in NJ for my birthday, strangely located in the hood (Camden). I was going to order alcohol, until I saw on the menu "BYOB". WTF? Apparently liquor licenses are a pain, so a lot of restaurants are BYOB. I regularly learn something new about this state that makes me wtf.

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